AORTIC GRAFT INFECTION: A HYBRID AND STAGED SOLUTION

Authors

  • Tony R. Soares Department of Vascular Surgery, Hospital Santa Maria, Lisbon, Portugal; Lisbon Academic Medical Centre, Lisbon, Portugal
  • Pedro Amorim Department of Vascular Surgery, Hospital Santa Maria, Lisbon, Portugal; Lisbon Academic Medical Centre, Lisbon, Portugal
  • Viviana Manuel Department of Vascular Surgery, Hospital Santa Maria, Lisbon, Portugal; Lisbon Academic Medical Centre, Lisbon, Portugal
  • Carlos Martins Department of Vascular Surgery, Hospital Santa Maria, Lisbon, Portugal; Lisbon Academic Medical Centre, Lisbon, Portugal
  • Pedro Martins Department of Vascular Surgery, Hospital Santa Maria, Lisbon, Portugal; Lisbon Academic Medical Centre, Lisbon, Portugal
  • Luís Mendes Pedro Department of Vascular Surgery, Hospital Santa Maria, Lisbon, Portugal; Lisbon Academic Medical Centre, Lisbon, Portugal; University of Lisbon, Lisbon, Portugal

DOI:

https://doi.org/10.48750/acv.249

Keywords:

aortic graft infection, aorto-bifemoral bypass, peripheral arterial disease, visceral bypass, hybrid surgery

Abstract

Introduction: Aortic graft infection (AGI) is a life-threatening condition and a therapeutic challenge for vascular surgeons. We report a case of a complex AGI managed by a hybrid and staged strategy.

Methods: Data related to the present case report were collected from hospital medical records.

Results: A 51-year-old male patient, submitted 5 years ago to prosthetic aorto-bifemoral and superior mesenteric artery (SMA) bypass to treat aorto-iliac and visceral occlusive disease and a recent history of a right femoral anastomotic pseudoaneurysm managed by open surgery, was admitted to our emergency room with a left femoral anastomotic pseudoaneurysm and inflammatory signs on the right groin. The diagnostic workup (angio-CT and PET-Scan) strongly suggested infection of the aorto-bifemoral graft.

A three-stage hybrid approach was then planned. In the first step, a left axillofemoral PTFE bypass was performed avoiding the infected area with ligation of the infected limb graft of the aorto-bifemoral bypass. Two weeks later, the patient was submitted to a successful endovascular recanalization of the SMA with implantation of a self-expandable bare metal stent, followed by a right axillofemoral PTFE bypass and ligation of the infected limb graft. One week later, the final stage included the exclusion of the proximal anastomosis of the visceral bypass with a covered stent in the SMA and a laparotomy for complete excision of the intrabdominal infected grafts with subsequent aortic ligation. The patient was discharged on the next three weeks on oral antimicrobial therapy. The post-op CT scan confirmed the patency of the SMA recanalization, both renal arteries, as well as the extra-anatomic bypasses to the lower limbs, with apparent resolution of the abdominal infection.

Conclusion: The reported case is very unusual and represents a challenge due to the presence of a SMA bypass associated to the AGI. Endovascular recanalization of the SMA occlusion made possible the total excision of the infected abdominal grafts.

Downloads

Download data is not yet available.

References

1. Berger, P. et al. Cumulative incidence of graft infection after primary prosthetic aortic reconstruction in the endovascular era. Eur. J. Vasc. Endovasc. Surg. 49, 581–585 (2015).
2. Shiraev, T. et al. Incidence, management and outcomes of aortic graft infection.R1 Aortic graft infection. Ann. Vasc. Surg. (2019). doi:10.1016/j.avsg.2019.01.027
3. Oderich, G. S. et al. Evolution from axillofemoral to in situ prosthetic reconstruction for the treatment of aortic graft infections at a single center. J. Vasc. Surg. 43, 1166–1174 (2006).
4. Heinola, I. et al. Editor’s Choice – Treatment of Aortic Prosthesis Infections by Graft Removal and In Situ Replacement with Autologous Femoral Veins and Fascial Strengthening. Eur. J. Vasc. Endovasc. Surg. 51, 232–239 (2016).
5. Kilic, A. et al. Management of infected vascular grafts. Vasc. Med. 21, 53–60 (2016).
6. Seeger, J. M. et al. Long-term outcome after treatment of aortic graft infection with staged extra-anatomic bypass grafting and aortic graft removal. J. Vasc. Surg. 32, 451–461 (2000).
7. Sharp, W. J. et al. The management of the infected aortic prosthesis: A current decade of experience. J. Vasc. Surg. 19, 844–850 (1994).
8. Yeager, R. A. et al. Improved results with conventional management of infrarenal aortic infection. J. Vasc. Surg. 30, 76–83 (1999).
9. Oderich, G. S. et al. In situ rifampin-soaked grafts with omental coverage and antibiotic suppression are durable with low reinfection rates in patients with aortic graft enteric erosion or fistula. J. Vasc. Surg. 53, 99-107.e7 (2011).
10. FitzGerald, S. F., Kelly, C. & Humphreys, H. Diagnosis and treatment of prosthetic aortic graft infections: confusion and inconsistency in the absence of evidence or consensus. J. Antimicrob. Chemother. 56, 996–999 (2005).
11. Calligaro, K. D., Veith, F. J., Yuan, J. G., Gargiulo, N. J. & Dougherty, M. J. Intra-abdominal aortic graft infection: complete or partial graft preservation in patients at very high risk. J. Vasc. Surg. 38, 1199–1204 (2003).
12. Morris, G. E. et al. Antibiotic irrigation and conservative surgery for major aortic graft infection. J. Vasc. Surg. 20, 88–95 (1994).
13. Lyons, O. T. A. et al. A 14-year Experience with Aortic Endograft Infection: Management and Results. Eur. J. Vasc. Endovasc. Surg. 46, 306–313 (2013).
14. Pistolese, G. R., Ippoliti, A., Tuccimei, I. & Lorido, A. Conservative treatment of aortic graft infection. Eur. J. Vasc. Endovasc. Surg. 14, 47–52 (1997).
15. O’Connor, S., Andrew, P., Batt, M. & Becquemin, J. P. A systematic review and meta-analysis of treatments for aortic graft infection. J. Vasc. Surg. 44, (2006).

Downloads

Published

2019-10-16

How to Cite

1.
Soares TR, Amorim P, Manuel V, Martins C, Martins P, Mendes Pedro L. AORTIC GRAFT INFECTION: A HYBRID AND STAGED SOLUTION. Angiol Cir Vasc [Internet]. 2019 Oct. 16 [cited 2024 Nov. 24];15(2):119-23. Available from: https://acvjournal.com/index.php/acv/article/view/249

Issue

Section

Clinical Case

Similar Articles

You may also start an advanced similarity search for this article.