THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR

  • Inês Antunes Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • Rui Machado Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto; Instituto de Ciências Biomédicas Abel Salazar - Universidade do Porto
  • Duarte Rego Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • Vítor Ferreira Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • João Gonçalves Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • Gabriela Teixeira Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • Carlos Veiga Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • Daniel Mendes Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto
  • Carlos Pereira Serviço Angiologia e Cirurgia Vascular Centro Hospitalar do Porto
  • Rui Almeida Serviço de Angiologia e Cirurgia Vascular – Centro Hospitalar Universitário do Porto; Instituto de Ciências Biomédicas Abel Salazar - Universidade do Porto
Keywords: Aortic aneurysm, EVAR, Thrombus, Acute kidney injury

Abstract

Introdution: Aneurysm neck morphology, in particular the presence of thrombus, may limit EVAR.

Objetives: Study whether the presence of neck thrombus and type of endoprothesis used (supra or infra-renal fixation) has impact on renal function of patients treated by EVAR at our institution.

Material/Methods: Retrospective analysis of the database of AAA treated by EVAR at our institution between December/2001 and December/2013. For each patient we evaluated creatinine/clearance in pre and postoperative periods. Of patients with renal function worsening, we selected those who had acute kidney injury (AKI) according to modified RIFLE criteria, and studied the relationship between AKI and neck thrombus and type of endoprosthesis used. From the database of 241 patients, renal failure patients at the procedure and those in which we didn’t have preoperative and postoperative renal function analyzes were excluded. Regarding the study of the relationship between endoprosthesis used and renal function: 127 were treated with supra-renal fixation endoprostheses, 74 with infra-renal fixation endoprostheses and 27 were excluded (thoracic endoprostheses or missed information). Regarding neck thrombus, we obtained this data for 190 patients.

Results: Regarding the presence of neck thrombus and renal function in postoperative period: of the 190 patients, 21 (11%) developed AKI and neck thrombus in > 25% and> 50% of neck circumference presented statistically significant relationship with the development of AKI (p = 0.045 and p = 0.010, respectively). Regarding the study of endoprostheses used, 14.2% of the patients treated with supra-renal fixation endoprostheses and 5.4% of those treated with infra-renal fixation developed AKI in postoperative period. However, this difference wasn’t statistically significant (p = 0.052). 

Discussion/Conclusions: Of our experience, neck thrombus is related to the development of AKI in postoperative period. Patients treated with supra-renal fixation endoprostheses developed more AKI in the postoperative period, but this difference was not statistically significant.

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Published
2018-12-02
Section
Original Article